Učitavanje...
Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex
Metformin is the most widely prescribed drug for the treatment of type-2 diabetes. However, knowledge of the full effects of metformin on biochemical pathways and processes in its primary target tissue, the liver, is limited. One established effect of metformin is to decrease cellular energy levels....
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| Izdano u: | Cell Metab |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299044/ https://ncbi.nlm.nih.gov/pubmed/28089566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.12.009 |
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