Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics

While translational regulation of p53 by the internal ribosome entry site (IRES) at its 5′-untranslated region following DNA damage has been widely accepted, the detailed mechanism underlying the translational control of p53 by its IRES sequence is still poorly understood. In this review, we will fo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ji, Bai, Harris, Benjamin R. E., Liu, Yahui, Deng, Yibin, Gradilone, Sergio A., Cleary, Margot P., Liu, Jianhua, Yang, Da-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297727/
https://ncbi.nlm.nih.gov/pubmed/28054974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010093
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