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Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma

Molecule-targeted therapy, such as sorafenib, is one of the effectively therapeutic options for advanced hepatocellular carcinoma (HCC). However, acquired resistance to sorafenib has been found in some HCC patients, resulting in poor prognosis. It is reported that PD-L1 and DNA methyltransferases (D...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Liu, Jianhua, Liu, Yahui, Meng, Lingyu, Liu, Kai, Ji, Bai
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561980/
https://ncbi.nlm.nih.gov/pubmed/28627705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5722
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