Translational Control Protein 80 Stimulates IRES-Mediated Translation of p53 mRNA in Response to DNA Damage

Synthesis of the p53 tumor suppressor increases following DNA damage. This increase and subsequent activation of p53 are essential for the protection of normal cells against tumorigenesis. We previously discovered an internal ribosome entry site (IRES) that is located at the 5′-untranslated region (...

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Vydáno v:Biomed Res Int
Hlavní autoři: Halaby, Marie-Jo, Li, Yan, Harris, Benjamin R., Jiang, Shuxia, Miskimins, W. Keith, Cleary, Margot P., Yang, Da-Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529924/
https://ncbi.nlm.nih.gov/pubmed/26273641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/708158
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