Innate Immunity Stimulation via Toll-Like Receptor 9 Ameliorates Vascular Amyloid Pathology in Tg-SwDI Mice with Associated Cognitive Benefits

Alzheimer's disease (AD) is characterized by the presence of parenchymal amyloid-β (Aβ) plaques, cerebral amyloid angiopathy (CAA) and neurofibrillary tangles. Currently there are no effective treatments for AD. Immunotherapeutic approaches under development are hampered by complications relate...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Scholtzova, Henrieta, Do, Eileen, Dhakal, Shleshma, Sun, Yanjie, Liu, Shan, Mehta, Pankaj D., Wisniewski, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296786/
https://ncbi.nlm.nih.gov/pubmed/28123027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1967-16.2016
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