エクスポート完了 — 
ロード中...

N,N Dimethylacetamide a drug excipient that acts as bromodomain ligand for osteoporosis treatment

N,N-Dimethylacetamide (DMA) is a water-miscible solvent, FDA approved as excipient and therefore widely used as drug-delivery vehicle. As such, DMA should be devoid of any bioactivity. Here we report that DMA is epigenetically active since it binds bromodomains and inhibits osteoclastogenesis and in...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Ghayor, Chafik, Gjoksi, Bebeka, Dong, Jing, Siegenthaler, Barbara, Caflisch, Amedeo, Weber, Franz E.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296751/
https://ncbi.nlm.nih.gov/pubmed/28176838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42108
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!