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The Release of the Bromodomain Ligand N,N-Dimethylacetamide Adds Bioactivity to a Resorbable Guided Bone Regeneration Membrane in a Rabbit Calvarial Defect Model

N,N-Dimethylacetamide (DMA) is FDA approved as an excipient and is used as drug-delivery vehicle. Due to its amphipathic nature and diverse bioactivities, it appears to be a good combination of biodegradable poly-lactide-co-glycolide (PLGA)-based guided bone regeneration membranes. Here we show that...

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Bibliographic Details
Published in:Materials (Basel)
Main Authors: Siegenthaler, Barbara, Ghayor, Chafik, Ruangsawasdi, Nisarat, Weber, Franz E.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7040842/
https://ncbi.nlm.nih.gov/pubmed/31973011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma13030501
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