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The Bromodomain Inhibitor N-Methyl pyrrolidone Prevents Osteoporosis and BMP-Triggered Sclerostin Expression in Osteocytes

(1) Background: In an adult skeleton, bone is constantly renewed in a cycle of bone resorption, followed by bone formation. This coupling process, called bone remodeling, adjusts the quality and quantity of bone to the local needs. It is generally accepted that osteoporosis develops when bone resorp...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Siegenthaler, Barbara, Ghayor, Chafik, Gjoksi-Cosandey, Bebeka, Ruangsawasdi, Nisarat, Weber, Franz E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275050/
https://ncbi.nlm.nih.gov/pubmed/30366476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113332
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