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Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals
Centrosome amplification is a common feature of human tumors, but whether this is a cause or a consequence of cancer remains unclear. Here, we test the consequence of centrosome amplification by creating mice in which centrosome number can be chronically increased in the absence of additional geneti...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296221/ https://ncbi.nlm.nih.gov/pubmed/28132847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.12.022 |
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