Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

BACKGROUND: Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Chu, Cindy S., Bancone, Germana, Moore, Kerryn A., Win, Htun Htun, Thitipanawan, Niramon, Po, Christina, Chowwiwat, Nongnud, Raksapraidee, Rattanaporn, Wilairisak, Pornpimon, Phyo, Aung Pyae, Keereecharoen, Lily, Proux, Stéphane, Charunwatthana, Prakaykaew, Nosten, François, White, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295665/
https://ncbi.nlm.nih.gov/pubmed/28170391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002224
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