Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

BACKGROUND: Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac...

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Foilsithe in:PLoS Med
Main Authors: Chu, Cindy S., Bancone, Germana, Moore, Kerryn A., Win, Htun Htun, Thitipanawan, Niramon, Po, Christina, Chowwiwat, Nongnud, Raksapraidee, Rattanaporn, Wilairisak, Pornpimon, Phyo, Aung Pyae, Keereecharoen, Lily, Proux, Stéphane, Charunwatthana, Prakaykaew, Nosten, François, White, Nicholas J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295665/
https://ncbi.nlm.nih.gov/pubmed/28170391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002224
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