Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

BACKGROUND: Radical cure of Plasmodium vivax malaria with 8-aminoquinolines (primaquine or tafenoquine) is complicated by haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac...

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Pubblicato in:PLoS Med
Autori principali: Chu, Cindy S., Bancone, Germana, Moore, Kerryn A., Win, Htun Htun, Thitipanawan, Niramon, Po, Christina, Chowwiwat, Nongnud, Raksapraidee, Rattanaporn, Wilairisak, Pornpimon, Phyo, Aung Pyae, Keereecharoen, Lily, Proux, Stéphane, Charunwatthana, Prakaykaew, Nosten, François, White, Nicholas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295665/
https://ncbi.nlm.nih.gov/pubmed/28170391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002224
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