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Single Low Dose Primaquine (0.25mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects

BACKGROUND: Primaquine is the only drug consistently effective against mature gametocytes of Plasmodium falciparum. The transmission blocking dose of primaquine previously recommended was 0.75mg/kg (adult dose 45mg) but its deployment was limited because of concerns over haemolytic effects in patien...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bancone, Germana, Chowwiwat, Nongnud, Somsakchaicharoen, Raweewan, Poodpanya, Lalita, Moo, Paw Khu, Gornsawun, Gornpan, Kajeechiwa, Ladda, Thwin, May Myo, Rakthinthong, Santisuk, Nosten, Suphak, Thinraow, Suradet, Nyo, Slight Naw, Ling, Clare L., Wiladphaingern, Jacher, Kiricharoen, Naw Lily, Moore, Kerryn A., White, Nicholas J., Nosten, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807095/
https://ncbi.nlm.nih.gov/pubmed/27010542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151898
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