Single Low Dose Primaquine (0.25mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects

BACKGROUND: Primaquine is the only drug consistently effective against mature gametocytes of Plasmodium falciparum. The transmission blocking dose of primaquine previously recommended was 0.75mg/kg (adult dose 45mg) but its deployment was limited because of concerns over haemolytic effects in patien...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Bancone, Germana, Chowwiwat, Nongnud, Somsakchaicharoen, Raweewan, Poodpanya, Lalita, Moo, Paw Khu, Gornsawun, Gornpan, Kajeechiwa, Ladda, Thwin, May Myo, Rakthinthong, Santisuk, Nosten, Suphak, Thinraow, Suradet, Nyo, Slight Naw, Ling, Clare L., Wiladphaingern, Jacher, Kiricharoen, Naw Lily, Moore, Kerryn A., White, Nicholas J., Nosten, Francois
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807095/
https://ncbi.nlm.nih.gov/pubmed/27010542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151898
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