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Tsc2 is not a critical target of Akt during normal Drosophila development

Signaling by insulin and target of rapamycin are both required for cell growth, but their interrelationships remain poorly defined. It was reported that Akt, an essential component of the insulin pathway, stimulates growth by phosphorylating and inhibiting tuberous sclerosis complex 2 (TSC2). Here w...

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Detalhes bibliográficos
Main Authors: Dong, Jixin, Pan, Duojia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529535/
https://ncbi.nlm.nih.gov/pubmed/15466161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1240504
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