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Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases

DNA replication is constantly challenged by DNA lesions, noncanonical DNA structures and difficult-to-replicate DNA sequences. Two major strategies to rescue a stalled replication fork and to ensure continuous DNA synthesis are: (1) template switching and recombination-dependent DNA synthesis; and (...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Zhao, Linlin, Washington, M. Todd
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295019/
https://ncbi.nlm.nih.gov/pubmed/28075396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8010024
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