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Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases

DNA replication is constantly challenged by DNA lesions, noncanonical DNA structures and difficult-to-replicate DNA sequences. Two major strategies to rescue a stalled replication fork and to ensure continuous DNA synthesis are: (1) template switching and recombination-dependent DNA synthesis; and (...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Zhao, Linlin, Washington, M. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295019/
https://ncbi.nlm.nih.gov/pubmed/28075396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8010024
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