Alpha-lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice

Hypothermia is a key symptom of sepsis, but the mechanism(s) leading to hypothermia during sepsis is largely unknown and thus no effective therapy is available for hypothermia. Therefore, it is important to investigate the mechanisms and develop effective therapeutic methods. Lipopolysaccharide (LPS...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Hiller, Sylvia, DeKroon, Robert, Xu, Longquan, Robinette, Jennifer, Winnik, Witold, Alzate, Oscar, Simington, Stephen, Maeda, Nobuyo, Yi, Xianwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293729/
https://ncbi.nlm.nih.gov/pubmed/24675228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.022
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