Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells

Murine leukemia virus (MLV)-derived vectors are widely used for hematopoietic stem cell (HSC) gene transfer, but lentiviral vectors such as the simian immunodeficiency virus (SIV) may allow higher efficiency transfer and better expression. Recent studies in cell lines have challenged the notion that...

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Detalhes bibliográficos
Main Authors: Hematti, Peiman, Hong, Bum-Kee, Ferguson, Cole, Adler, Rima, Hanawa, Hideki, Sellers, Stephanie, Holt, Ingeborg E, Eckfeldt, Craig E, Sharma, Yugal, Schmidt, Manfred, von Kalle, Christof, Persons, Derek A, Billings, Eric M, Verfaillie, Catherine M, Nienhuis, Arthur W, Wolfsberg, Tyra G, Dunbar, Cynthia E, Calmels, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529319/
https://ncbi.nlm.nih.gov/pubmed/15550989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020423
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