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MLV integration site selection is driven by strong enhancers and active promoters

Retroviruses integrate into the host genome in patterns specific to each virus. Understanding the causes of these patterns can provide insight into viral integration mechanisms, pathology and genome evolution, and is critical to the development of safe gene therapy vectors. We generated murine leuke...

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書誌詳細
主要な著者: LaFave, Matthew C., Varshney, Gaurav K., Gildea, Derek E., Wolfsberg, Tyra G., Baxevanis, Andreas D., Burgess, Shawn M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985626/
https://ncbi.nlm.nih.gov/pubmed/24464997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1399
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