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MLV integration site selection is driven by strong enhancers and active promoters
Retroviruses integrate into the host genome in patterns specific to each virus. Understanding the causes of these patterns can provide insight into viral integration mechanisms, pathology and genome evolution, and is critical to the development of safe gene therapy vectors. We generated murine leuke...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985626/ https://ncbi.nlm.nih.gov/pubmed/24464997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1399 |
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