A Central Role for HLA-DR3 in Anti-Smith Antibody Responses and Glomerulonephritis in a Transgenic Mouse Model of Spontaneous Lupus

MHC, especially HLA-DR3 and HLA-DR2, is one of the most important genetic susceptibility regions for systemic lupus erythematosus. Human studies to understand the role of specific HLA alleles in disease pathogenesis have been hampered by the presence of strong linkage disequilibrium in this region....

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Publicado no:J Immunol
Main Authors: Chowdhary, Vaidehi R., Dai, Chao, Tilahun, Ashenafi Y., Hanson, Julie A., Smart, Michele K., Grande, Joseph P., Rajagopalan, Govindarajan, Fu, Shu-Man, David, Chella S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292932/
https://ncbi.nlm.nih.gov/pubmed/26475924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501073
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