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Spontaneous lupus-like syndrome in HLA-DQ2 Transgenic Mice with a Mixed Genetic Background
To investigate the role of HLA-DQ2 in the pathogenesis of associated immune disorders, we generated transgenic mice that expressed HLA-DQ2 in the absence of endogenous murine class II molecules (AE°DQ2). These AE°DQ2 mice with a mixed genetic background spontaneously developed skin lesions on their...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913253/ https://ncbi.nlm.nih.gov/pubmed/20142296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203309360546 |
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