HLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmD

Although systemic lupus erythematosus (SLE) is a multigenic autoimmune disorder, HLA-D is the most dominant genetic susceptibility locus. This study was undertaken to investigate the hypothesis that microbial peptides bind HLA-DR3 and activate T cells reactive with lupus autoantigens. Using HLA-DR3...

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Autores principales: Deshmukh, Umesh S, Sim, Davis L, Dai, Chao, Kannapell, Carol J, Gaskin, Felicia, Rajagopalan, Govindarajan, David, Chella S, Fu, Shu Man
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372418/
https://ncbi.nlm.nih.gov/pubmed/21868195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.07.002
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