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Nature of T cell epitopes in lupus antigens and HLA-DR determines autoantibody initiation and diversification
OBJECTIVES: The generation of systemic lupus erythematosus (SLE)-related autoantibodies have been shown to be T cell dependent and antigen driven with HLA-DR restriction. In this study, the initiating antigen(s) and the mechanism of autoantibody diversification were investigated. METHODS: T cell epi...
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| Publicado no: | Ann Rheum Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377330/ https://ncbi.nlm.nih.gov/pubmed/30254034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214125 |
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