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HLA-DR3 restricted T cell epitope mimicry in induction of autoimmune response to lupus-associated antigen SmD
Although systemic lupus erythematosus (SLE) is a multigenic autoimmune disorder, HLA-D is the most dominant genetic susceptibility locus. This study was undertaken to investigate the hypothesis that microbial peptides bind HLA-DR3 and activate T cells reactive with lupus autoantigens. Using HLA-DR3...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372418/ https://ncbi.nlm.nih.gov/pubmed/21868195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.07.002 |
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