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Prediction of CYP2D6 phenotype from genotype across world populations
PURPOSE: Owing to its highly polymorphic nature and major contribution to the metabolism and bioactivation of numerous clinically used drugs, CYP2D6 is one of the most extensively studied drug-metabolizing enzymes and pharmacogenes. CYP2D6 alleles confer no, decreased, normal, or increased activity...
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| Published in: | Genet Med |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292679/ https://ncbi.nlm.nih.gov/pubmed/27388693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2016.80 |
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