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Natural IgM and the Development of B Cell-Mediated Autoimmune Diseases
Most serum immunoglobulin M (IgM) is “natural IgM,” which is produced apparently spontaneously by a distinct subset of B cells requiring no exogenous antigenic or microbial stimuli. Natural IgM is an evolutionarily conserved molecule and reacts with a variety of epitopes expressed on both self- and...
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| Publicado en: | Crit Rev Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292326/ https://ncbi.nlm.nih.gov/pubmed/27910766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/CritRevImmunol.2016018175 |
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