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Natural IgM and the Development of B Cell-Mediated Autoimmune Diseases

Most serum immunoglobulin M (IgM) is “natural IgM,” which is produced apparently spontaneously by a distinct subset of B cells requiring no exogenous antigenic or microbial stimuli. Natural IgM is an evolutionarily conserved molecule and reacts with a variety of epitopes expressed on both self- and...

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Podrobná bibliografie
Vydáno v:Crit Rev Immunol
Hlavní autoři: Nguyen, Trang T. T., Baumgarth, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292326/
https://ncbi.nlm.nih.gov/pubmed/27910766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/CritRevImmunol.2016018175
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