TMC125, a Novel Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor Active against Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Human Immunodeficiency Virus Type 1

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are potent inhibitors of human immunodeficiency virus type 1 (HIV-1); however, currently marketed NNRTIs rapidly select resistant virus, and cross-resistance within the class is extensive. A parallel screening strategy was applied to test candi...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Andries, Koen, Azijn, Hilde, Thielemans, Theo, Ludovici, Donald, Kukla, Michael, Heeres, Jan, Janssen, Paul, De Corte, Bart, Vingerhoets, Johan, Pauwels, Rudi, de Béthune, Marie-Pierre
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529207/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15561844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.12.4680-4686.2004
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