A nonnucleoside reverse transcriptase inhibitor active on human immunodeficiency virus type 1 isolates resistant to related inhibitors.

Pyridinone derivatives are potent and specific inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and HIV-1 replication in cell culture. However, the potential clinical usefulness of these compounds as monotherapeutic agents may be limited by the selection of inhibi...

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Hlavní autoři: Goldman, M E, O'Brien, J A, Ruffing, T L, Schleif, W A, Sardana, V V, Byrnes, V W, Condra, J H, Hoffman, J M, Emini, E A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC187857/
https://ncbi.nlm.nih.gov/pubmed/7685996
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