A nonnucleoside reverse transcriptase inhibitor active on human immunodeficiency virus type 1 isolates resistant to related inhibitors.

Pyridinone derivatives are potent and specific inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and HIV-1 replication in cell culture. However, the potential clinical usefulness of these compounds as monotherapeutic agents may be limited by the selection of inhibi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Goldman, M E, O'Brien, J A, Ruffing, T L, Schleif, W A, Sardana, V V, Byrnes, V W, Condra, J H, Hoffman, J M, Emini, E A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.947
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