Susceptibilities of human immunodeficiency virus type 1 enzyme and viral variants expressing multiple resistance-engendering amino acid substitutions to reserve transcriptase inhibitors.

To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination nucleoside and nonnucleoside reverse transcriptase inhibitor therapy, we constructed a series of mutant reverse transcriptase enzymes and viruses that coexpressed various combi...

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Bibliographic Details
Main Authors: Byrnes, V W, Emini, E A, Schleif, W A, Condra, J H, Schneider, C L, Long, W J, Wolfgang, J A, Graham, D J, Gotlib, L, Schlabach, A J
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC188219/
https://ncbi.nlm.nih.gov/pubmed/7522428
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