Susceptibilities of human immunodeficiency virus type 1 enzyme and viral variants expressing multiple resistance-engendering amino acid substitutions to reserve transcriptase inhibitors.

To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination nucleoside and nonnucleoside reverse transcriptase inhibitor therapy, we constructed a series of mutant reverse transcriptase enzymes and viruses that coexpressed various combi...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Byrnes, V W, Emini, E A, Schleif, W A, Condra, J H, Schneider, C L, Long, W J, Wolfgang, J A, Graham, D J, Gotlib, L, Schlabach, A J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7522428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.6.1404
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