Evaluation of the Role of Constitutive Isocitrate Lyase Activity in Yersinia pestis Infection of the Flea Vector and Mammalian Host

Yersinia pestis, unlike the closely related Yersinia pseudotuberculosis, constitutively produces isocitrate lyase (ICL). Here we show that the Y. pestis aceA homologue encodes ICL and is required for growth on acetate but not for flea infection or virulence in mice. Thus, deregulation of the glyoxyl...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Sebbane, Florent, Jarrett, Clayton O., Linkenhoker, Jan R., Hinnebusch, B. Joseph
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2004
Matèries:	Molecular Pathogenesis
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529124/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15557663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.12.7334-7337.2004
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