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A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine. Reprogramming is a stepwise process with well-defined stages of initiation, maturation and stabilisation which are critically dependent on interactions between key pluripotency...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Neganova, Irina, Chichagova, Valeria, Armstrong, Lyle, Lako, Majlinda
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290526/
https://ncbi.nlm.nih.gov/pubmed/28155868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41693
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