Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos

CRISPR-Cas9 is a powerful new tool for genome editing, but this technique creates mosaic mutations that affect the efficiency and precision of its ability to edit the genome. Reducing mosaic mutations is particularly important for gene therapy and precision genome editing. Although the mechanisms un...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tu, Zhuchi, Yang, Weili, Yan, Sen, Yin, An, Gao, Jinquan, Liu, Xudong, Zheng, Yinghui, Zheng, Jiezhao, Li, Zhujun, Yang, Su, Li, Shihua, Guo, Xiangyu, Li, Xiao-Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290468/
https://ncbi.nlm.nih.gov/pubmed/28155910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42081
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker