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CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases

Animal models are extremely valuable to help us understand the pathogenesis of neurodegenerative disorders and to find treatments for them. Since large animals are more like humans than rodents, they make good models to identify the important pathological events that may be seen in humans but not in...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Tu, Zhuchi, Yang, Weili, Yan, Sen, Guo, Xiangyu, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524001/
https://ncbi.nlm.nih.gov/pubmed/26238861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0031-x
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