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A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity
Multivesicular body morphology and size are controlled in part by PtdIns(3,5)P(2), produced in mammalian cells by PIKfyve-directed phosphorylation of PtdIns(3)P. Here we identify human Vac14 (hVac14), an evolutionarily conserved protein, present in all eukaryotes but studied principally in yeast thu...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology
2004
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529046/ https://ncbi.nlm.nih.gov/pubmed/15542851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10437-10447.2004 |
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