A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity

Multivesicular body morphology and size are controlled in part by PtdIns(3,5)P(2), produced in mammalian cells by PIKfyve-directed phosphorylation of PtdIns(3)P. Here we identify human Vac14 (hVac14), an evolutionarily conserved protein, present in all eukaryotes but studied principally in yeast thu...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Sbrissa, Diego, Ikonomov, Ognian C., Strakova, Jana, Dondapati, Rajeswari, Mlak, Krzysztof, Deeb, Robert, Silver, Robert, Shisheva, Assia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2004
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10437-10447.2004
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