A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity

Multivesicular body morphology and size are controlled in part by PtdIns(3,5)P(2), produced in mammalian cells by PIKfyve-directed phosphorylation of PtdIns(3)P. Here we identify human Vac14 (hVac14), an evolutionarily conserved protein, present in all eukaryotes but studied principally in yeast thu...

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Hauptverfasser: Sbrissa, Diego, Ikonomov, Ognian C., Strakova, Jana, Dondapati, Rajeswari, Mlak, Krzysztof, Deeb, Robert, Silver, Robert, Shisheva, Assia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC529046/
https://ncbi.nlm.nih.gov/pubmed/15542851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10437-10447.2004
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