PIKfyve-ArPIKfyve-Sac3 Core Complex: CONTACT SITES AND THEIR CONSEQUENCE FOR Sac3 PHOSPHATASE ACTIVITY AND ENDOCYTIC MEMBRANE HOMEOSTASIS

The phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P(2)) metabolizing enzymes, the kinase PIKfyve and the phosphatase Sac3, constitute a single multiprotein complex organized by the PIKfyve regulator ArPIKfyve and its ability to homodimerize. We previously established that PIKfyve is activated wi...

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Detalles Bibliográficos
Autores principales: Ikonomov, Ognian C., Sbrissa, Diego, Fenner, Homer, Shisheva, Assia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Molecular Basis of Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791009/
https://ncbi.nlm.nih.gov/pubmed/19840946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.037515
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