CpG-ODN Shapes Alum Adjuvant Activity Signaling via MyD88 and IL-10

Aluminum-containing adjuvants usually referred as Alum are considered as T helper type-2 (Th2) adjuvants, while agonists of toll-like receptors (TLRs) are viewed as adjuvants that favor Th1/Th17 immunity. Alum has been used in numerous vaccine formulations; however, its undesired pro-Th2 adjuvant ac...

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Publicat a:Front Immunol
Autors principals: Mirotti, Luciana, Alberca Custódio, Ricardo Wesley, Gomes, Eliane, Rammauro, Florencia, de Araujo, Eliseu Frank, Garcia Calich, Vera Lucia, Russo, Momtchilo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289984/
https://ncbi.nlm.nih.gov/pubmed/28220116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00047
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