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CpG-ODN Signaling via Dendritic Cells-Expressing MyD88, but Not IL-10, Inhibits Allergic Sensitization

Allergen-specific T helper (Th)2 cells orchestrate upon allergen challenge the development of allergic eosinophilic lung inflammation. Sensitization with alum adjuvant, a type 2 adjuvant, has been used extensively in animal models of allergic lung disease. In contrast, type 1 adjuvants like CpG-ODN,...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Alberca, Ricardo Wesley, Gomes, Eliane, Russo, Momtchilo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8310155/
https://ncbi.nlm.nih.gov/pubmed/34358159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9070743
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