Dendritic Cells Expressing MyD88 Molecule Are Necessary and Sufficient for CpG-Mediated Inhibition of IgE Production In Vivo

Elevated levels of immunoglobulin E (IgE) are associated with allergies and other immunological disorders. Sensitization with alum adjuvant favours IgE production while CpG-ODN adjuvant, a synthetic toll-like receptor 9 (TLR9) agonist, inhibits it. The cellular mechanisms underlying in vivo TLR regu...

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Udgivet i:Cells
Main Authors: Alberca Custodio, Ricardo W., Mirotti, Luciana, Gomes, Eliane, Nunes, Fernanda P.B., S. Vieira, Raquel, Graça, Luís, R. Almeida, Rafael, S. Câmara, Niels O., Russo, Momtchilo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829343/
https://ncbi.nlm.nih.gov/pubmed/31569343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101165
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