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Inhibiting thyrotropin/insulin‐like growth factor 1 receptor crosstalk to treat Graves' ophthalmopathy: studies in orbital fibroblasts in vitro

BACKGROUND AND PURPOSE: Crosstalk between thyrotropin (TSH) receptors and insulin‐like growth factor 1 (IGF‐1) receptors initiated by activation of TSH receptors could be important in the development of Graves' ophthalmopathy (GO). Specifically, TSH receptor activation alone is sufficient to st...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Place, Robert F, Krieger, Christine C, Neumann, Susanne, Gershengorn, Marvin C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289943/
https://ncbi.nlm.nih.gov/pubmed/27987211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13693
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