Preclinical Modeling of KIF5B-RET Fusion Lung Adenocarcinoma

RET fusions have been found in lung adenocarcinoma, of which KIF5B-RET is the most prevalent. We established inducible KIF5B-RET transgenic mice and KIF5B-RET-dependent cell lines for preclinical modeling of KIF5B-RET-associated lung adenocarcinoma. Dox-induced CCSP-rtTA/tetO-KIF5B-RET transgenic mi...

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Publicat a:Mol Cancer Ther
Autors principals: Huang, Qingling, Schneeberger, Valentina E., Luetteke, Noreen, Jin, Chengliu, Afzal, Roha, Budzevich, Mikalai M., Makanji, Rikesh J., Martinez, Gary V., Shen, Tao, Zhao, Lichao, Fung, Kar-Ming, Haura, Eric B., Coppola, Domenico, Wu, Jie
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289739/
https://ncbi.nlm.nih.gov/pubmed/27496134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0258
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