SHP2(E76K) mutant promotes lung tumorigenesis in transgenic mice

Lung cancer is a major disease carrying heterogeneous molecular lesions and many of them remain to be analyzed functionally in vivo. Gain-of-function (GOF) SHP2 (PTPN11) mutations have been found in various types of human cancer, including lung cancer. However, the role of activating SHP2 mutants in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schneeberger, Valentina E., Luetteke, Noreen, Ren, Yuan, Berns, Hartmut, Chen, Liwei, Foroutan, Parastou, Martinez, Gary V., Haura, Eric B., Chen, Jiandong, Coppola, Domenico, Wu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123642/
https://ncbi.nlm.nih.gov/pubmed/24480804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu025
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados