A carregar...
SHP2(E76K) MUTANT CONFERS CYTOKINE-INDEPENDENT SURVIVAL OF TF-1 MYELOID CELLS BY UP-REGULATING BCL-X(L)
Shp2 has been known to mediate growth factor-stimulated cell proliferation but its role in cell survival is less clear. Gain-of-function Shp2 mutants such as Shp2(E76K) are associated with myeloid leukemias. We found that Shp2(E76K) could transform cytokine-dependent human TF-1 myeloid cells into cy...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000740/ https://ncbi.nlm.nih.gov/pubmed/17942397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705789200 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|