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Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus

Ergosterol, a fungus-specific sterol enriched in cell plasma membranes, is an effective antifungal drug target. However, current knowledge of the ergosterol biosynthesis process in the saprophytic human fungal pathogen Aspergillus fumigatus remains limited. In this study, we found that two endoplasm...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Appl Environ Microbiol
मुख्य लेखकों: Long, Nanbiao, Xu, Xiaoling, Zeng, Qiuqiong, Sang, Hong, Lu, Ling
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288824/
https://ncbi.nlm.nih.gov/pubmed/27986720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02924-16
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