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The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility

Ergosterol is a major and specific component of the fungal plasma membrane, and thus, the cytochrome P450 enzymes (Erg proteins) that catalyze ergosterol synthesis have been selected as valuable targets of azole antifungals. However, the opportunistic pathogen Aspergillus fumigatus has developed wor...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:mBio
Main Authors: Song, Jinxing, Zhai, Pengfei, Zhang, Yuanwei, Zhang, Caiyun, Sang, Hong, Han, Guanzhu, Keller, Nancy P., Lu, Ling
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Microbiology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791848/
https://ncbi.nlm.nih.gov/pubmed/26908577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01919-15
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