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Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
Aptamers are powerful candidates for molecular imaging applications due to a number of attractive features, including rapid blood clearance and tumor penetration. We carried out structure–activity relationship (SAR) studies with the Tenascin-C binding aptamer TTA1, which is a promising candidate for...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC528785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15509871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh862 |
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