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Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
Aptamers are powerful candidates for molecular imaging applications due to a number of attractive features, including rapid blood clearance and tumor penetration. We carried out structure–activity relationship (SAR) studies with the Tenascin-C binding aptamer TTA1, which is a promising candidate for...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC528785/ https://ncbi.nlm.nih.gov/pubmed/15509871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh862 |
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